Havana is the main setting in Cuba. This part of the island is where most of its historical Mafia interaction took place...kinda like in The Godfather. That and of course, this is where the CIA historically did all their hi-jinks against Fidel Castro as well. Thus, Havana is a 'location of interest' to the CIA after Castro took power and ousted the Mafia. The main cast of the Crime and Beauty series usually have a mission or two in Havana.